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Venous Thromboembolism Prophylaxis in the Acute Medically Ill Patient


Venous thromboembolism (VTE) is a common diagnosis for many hospitalized, medically ill, non-surgical patients. VTE is a serious concern in that it is associated with significant morbidity and mortality.1 A VTE diagnosis is particularly significant for patients because the risk of recurrence is great, and patients require adequate monitoring and management. There has been a substantial paradigm shift from a time when almost all medically ill patients received prophylaxis to current guidelines recommending a tailored approach according to risk stratification guidance.

SHM has developed a compendium, supplemental suite of resources, and educational modules to review evidence-based strategies for appropriately selecting which VTE patients require prophylaxis as well as identifying appropriate candidates for extended prophylaxis. 

Learning Materials include:

  • Compendium discussing VTE risk stratification frameworks and practice, VTE prophylactic options for the hospitalized, medically ill patient and considerations for post-discharge prophylaxis, and strategies for thromboembolic prevention in COVID-19 patients
  • Recorded Webinar Modules:
    1. Risk Stratification, Guidance for Prophylaxis 
    2. In-Hospital VTE Prophylaxis 
    3. Post-Discharge VTE Prophylaxis 
    4. COVID-19 and Thrombosis 
  • Sample VTE Prophylaxis Order Set Specifications
  • Eligibility Checklist for Post-Discharge VTE Prophylaxis
  • Risk Assessment Models
  • Patient Educational Video


1Prandoni P, Noventa F, Ghirarduzzi A, et al. The risk of recurrent venous thromboembolism after discontinuing anticoagulation in patients with acute proximal deep vein thrombosis or pulmonary embolism. A prospective cohort study in 1,626 patients. Haematologica. 2007;92(2):199–205.